Illinois Fighting Illini - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 28, 2021 | vs Nebraska | REG | W | 30-22 | W | +6.5 | U | 52.5 |
| Sep 4, 2021 | vs Texas-San Antonio | REG | L | 37-30 | L | -4.5 | O | 52 |
| Sep 11, 2021 | @ Virginia | REG | L | 42-14 | L | +10.5 | U | 57 |
| Sep 17, 2021 | vs Maryland | REG | L | 20-17 | W | +7 | U | 61.5 |
| Sep 25, 2021 | @ Purdue | REG | L | 13-9 | W | +10.5 | U | 53 |
| Oct 2, 2021 | vs Charlotte | REG | W | 24-14 | P | -10 | U | 54 |
| Oct 9, 2021 | vs Wisconsin | REG | L | 24-0 | L | +12 | U | 42 |
| Oct 23, 2021 | @ Penn State | REG | W | 20-18 | W | +24.5 | U | 45.5 |
| Oct 30, 2021 | vs Rutgers | REG | L | 20-14 | L | +1.5 | U | 41.5 |
| Nov 6, 2021 | @ Minnesota | REG | W | 14-6 | W | +14.5 | U | 44 |
| Nov 20, 2021 | @ Iowa | REG | L | 33-23 | W | +12 | O | 38.5 |
| Nov 27, 2021 | vs Northwestern | REG | W | 47-14 | W | -7 | O | 44.5 |
