Cleveland Indians Favored by -180 Against Chicago White Sox on Wednesday

The Chicago White Sox will look to bolster their win total and reward those moneyline betting when the Cleveland Indians invade Guaranteed Rate Field on Wednesday.

It's a pitching duel between Dylan Covey for the Chicago White Sox (2-1 on the year) and Trevor Bauer for Cleveland Indians (5-4 so far).

Sportsbook Odds & Computer Pick

Sportsbooks such as Sportsbook had installed the Chicago White Sox as 170 moneyline underdogs in this particular MLB betting odds matchup. The total, meanwhile, was set early at 9 before betting at Sportsbook started to move the line.

Prediction-scoring formulas run on this game pick a potential 2.8-2.6 result in favor of the White Sox. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Cleveland Indians vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

23-42 Chicago battles the Indians, currently with a 35-30 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Cleveland injuries news.

It's a MLB baseball betting matchup between the No. 19-rated Chicago White Sox and the league No. 8-ranked Cleveland Indians, according to the latest MLB power poll here at Odds Shark.

Statistical Matchup

When it comes to getting on base, the visiting Cleveland Indians rank No. 7 at 8.77 hits per game. That compares with the Chicago White Sox No. 21 ranking in that category.

Defensively, Cleveland features the No. 8-rated defense on the road, allowing 3.82 runs per game. Chicago, meanwhile, comes in at No. 26 at home, scoring 3.77 runs per game.