OddsShark Top Sportsbooks

*Terms and Conditions apply to all bonus offers on this website. Please visit operator for details.

Chicago White Sox Host Houston Astros in MLB Baseball Betting Action

MLB wagering interest swings to the Houston Astros vs Chicago White Sox battle on Wednesday at U.S. Cellular Field as the White Sox try to pick up a win on home turf and reward those moneyline betting.

The Chicago White Sox will rely on Mat Latos to turn in a quality outing on the mound in this one, while Doug Fister will be his counterpart for the Houston Astros. Mat Latos is 5-0 this season, and Doug Fister is 3-3.

Opening Odds & Computer Pick

On the MLB moneyline for this betting odds matchup, Chicago sat as -120 favorites earlier in the day at Bovada. The over/under total was set at 8.5, according to MyBookie.

Handicapping models based on recent betting stats and prediction formulas pick a 6.5-5.0 win for the White Sox. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Houston Astros vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

The Chicago White Sox sport a record of 24-15 heading into this matchup, while the Houston Astros sit at 16-24 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Houston injuries news.

The Chicago White Sox vs Houston Astros odds would favor the White Sox if the betting lines were set according to our power ranks. Chicago is rated No. 3 in the current Odds Shark poll, while Houston is at No. 16.

Statistical Matchup

When it comes to getting on base, the visiting Houston Astros rank No. 23 at 7.93 hits per game. That compares with the Chicago White Sox No. 14 ranking in that category.

Defensively, Houston features the No. 29-rated defense on the road, allowing 6.1 runs per game. Chicago, meanwhile, comes in at No. 17 at home, scoring 4 runs per game.

Recent Outings Betting Recap

Houston needed extra innings to get the job done against the White Sox on Tuesday as the Astros defeated them 6-5 at U.S. Cellular Field.

Betting Trends
  • The total has gone OVER in 5 of Houston's last 5 games
  • Houston is 5-14 SU in its last 19 games on the road
  • The total has gone OVER in 5 of Houston's last 5 games on the road
  • Houston is 1-4 SU in its last 5 games when playing Chi White Sox
  • Chi White Sox is 1-5 SU in its last 6 games
  • The total has gone OVER in 6 of Chi White Sox's last 7 games
  • Chi White Sox is 7-3 SU in its last 10 games at home
  • The total has gone OVER in 4 of Chi White Sox's last 5 games at home

Next Betting Matchups

Houston at Chicago, Thursday, May 19th