The St. Louis Cardinals (61-50) are 8-0 SU in their last eight home games heading into this three-game series against the Milwaukee Brewers (60-50). St. Louis will try to extend its home winning streak with a victory as a Brewers vs Cardinals prediction favorite this Friday night in St. Louis.

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Brewers vs Cardinals Odds & Analysis

Opening Odds

The Cardinals opened as -152 favorites before moving up to St. Louis -165 while Milwaukee has settled in as a +140 road underdog. Betting action on the OVER as a popular Brewers vs Cardinals prediction drove the total up to eight runs after it opened at seven runs. The UNDER is 4-2 in St. Louis's last six home games against Milwaukee.

Starting Pitchers

Eric Lauer continued his solid 2022 campaign in Milwaukee's 5-1 win over the Cincinnati Reds last Friday night, pitching seven innings and allowing only one earned run. Lauer is now 8-3 with a 3.59 ERA and a 1.22 WHIP with 111 strikeouts in 112.2 innings pitched.

Jordan Montgomery had a successful outing in his first start with the Cardinals last Saturday, pitching five shutout innings against his former team to help St. Louis pick up a 1-0 win over the New York Yankees. Montgomery is 4-3 this season with a 3.53 ERA and a 1.08 WHIP across 22 starts.

Get the best Brewers vs Cardinals odds and lines available from our recommended sportsbooks for your favorite picks of the night

  • Best Spread
    -145
    +135
    MIL+1.5
    -1.5STL
  • Best Moneyline
    +152
    -160
    MIL
    STL
  • Best Total
    +100
    -115
    Over7.5
    7.5Under

Milwaukee Has Been Struggling On The Road

The Brewers snapped out of a 1-6 SU slump with back-to-back wins at home over the Tampa Bay Rays on Tuesday and Wednesday night. Milwaukee will try to carry the momentum of those two wins into this road series as the club is just 2-7 SU in its last nine games away from home.

Only a half-game separates these two NL Central rivals ahead of Friday's action. With the NL Wild card picture looking crowded at the top between the Atlanta Braves, Philadelphia Phillies and San Diego Padres, winning the division is clearly the best path to a playoff spot for both the Brewers and the Cardinals.

St. Louis's Pitching Has Hit A Snag This Week

The Cardinals came into this week on the heels of a 7-0 SU winning streak, but they dropped two out of three games against the Colorado Rockies, most recently losing 8-6 on Thursday night. St. Louis has allowed a whopping 9.5 runs per game over a 2-2 SU stretch in its last four games since surrendering only 1.33 runs in its previous six games.

It is worth noting that pitching staffs and bullpens struggle all the time in the thin air of Colorado. Bettors taking St. Louis as their Brewers vs Cardinals prediction will be counting on the Cardinals to get back on track in their return home.

Brewers vs Cardinals Pick & Insights

Brewers: Keys to Victory

Eric Lauer has historically struggled against the Cardinals with a 6.93 ERA and a 1.74 WHIP in 24.2 career innings pitched against them. Lauer will need to be better on Friday than he has been in the past against St. Louis to put Milwaukee in position to win as a Brewers vs Cardinals prediction.

Cardinals: Keys to Victory

The Cardinals have been dominant at home this season with a 35-20 SU record. If Montgomery is able to produce his usual five or six quality innings to get St. Louis's pitching back on track, Paul Goldschmidt and the offense should be able to take care of the rest en route to a Brewers vs Cardinals pick win.

MLB Computer Pick: Total will go OVER -120

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Shark Bites
  • Milwaukee is 1-6 SU in its last 7 games vs NL teams.
  • St. Louis is 38-18 SU as a favorite this season.
  • The OVER is 4-0 in St. Louis's last 4 games.
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