Framber Valdez's Astros favored in our Houston Astros and Philadelphia Phillies picks and odds

Phillies vs Astros Picks & Odds: Houston One Win Away From World Series Title

The Houston Astros (116-58) are 10-2 SU so far this postseason and are now one win over the Philadelphia Phillies (98-80) away from becoming the 2022 World Series Champions. The Astros will look to win the World Series by cashing in as a Phillies vs Astros prediction this Saturday night in Houston.

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Phillies vs Astros Sportsbook Odds

Sportsbook Odds

The Astros opened as -143 favorites at home in Game 6 and have settled in right above that with the Phillies vs Astros odds moving up just a bit to Houston -145. The Phillies will try to force a Game 7 with a win as +130 underdogs, and the total on Saturday is set at seven runs. The UNDER is 3-0-1 in the last four games in this series.

Starting Pitchers


Zack Wheeler gave up six hits and four earned runs across five innings pitched in Philadelphia's 5-2 loss to the Astros in Game 2 of the World Series last Saturday. Wheeler has started five games this postseason and carries a 2.67 ERA and a 0.73 WHIP over that stretch into this showdown with the Astros.

Framber Valdez pitched 6.1 innings and allowed only four hits and one earned run while striking out nine batters in Houston's Game 2 victory. Valdez has pitched 19 innings through three starts during the 2022 playoffs and has compiled a 1.42 ERA and a 0.95 WHIP in those three games.

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Philadelphia's Offense Has Cooled Off In Back-To-Back Losses

The Phillies appeared to have taken control of the series with their decisive 7-0 blowout win at home over the Astros in Game 3 on Tuesday night. But Houston responded by pitching a no-hitter in Game 4, and Philadelphia's offense only managed to generate two runs in a 3-2 loss in Game 5 on Thursday night.

Rhys Hoskins and J.T. Realmuto have each gone 0-for-9 in Philadelphia's last two games batting in the second and third spots in the lineup respectively. The Phillies are now just 1-3 SU over their last four games after having gone 4-0 SU in their previous four games.

Houston's Pitching And Defense Have Helped The Astros Take The Lead

Justin Verlander bounced back from his rough start in Game 1 to hold the Phillies to just one run in five innings of work, and the bullpen took care of the rest. The Astros also played some great defense throughout the win, highlighted by a huge stop by Trey Mancini at first base on a shot by Kyle Schwarber that would have tied the game for Philadelphia in the eighth inning.


The Astros enter Game 6 with a 60-27 SU record at home this season including a 5-1 SU record in Houston during the postseason. Houston will have two opportunities to win their first World Series since 2017 at home this weekend.

Phillies Player Prop: Bryce Harper Over 1.5 Total Bases (+149)

Bryce Harper has compiled two or more total bases from hits in 12 of his last 15 games this postseason. Houston's elite pitching staff and bullpen won't make things easy for Harper, but he's been too good in these playoffs to expect him not to make an impact in a potential elimination game.

Astros Player Prop: Framber Valdez Over 6.5 Strikeouts (+110)

Framber Valdez has struck out at least nine batters in three of his last four games. Those three games include 10 strikeouts in five innings against the Phillies on October 5 and nine strikeouts against them in Game 2. There is definitely value on this prop at a good price.

Phillies vs Astros Picks & Insights

Phillies: Keys To Victory

 The bounces that have been going Philadelphia's way all postseason long haven't been over the team's last two games. Philadelphia will need to get its offense going again, preferably with a hot start, to pull off an upset as a Phillies vs Astros prediction on Saturday night.

Astros: Keys To Victory

Houston has taken a 3-2 series lead in the World Series thanks to its outstanding pitching over the last two games. As long as Framber Valdez continues to pitch in the current form that he has had over the last month, there's a good chance Houston will cash in as a Phillies vs Astros pick in Game 6.

MLB Computer Picks: Astros -150 

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Shark Bites
  • Philadelphia is 2-5 SU in its last 7 games vs Houston.
  • Houston is 12-2 SU over its last 14 games.
  • The UNDER is 4-2 in Houston's last 6 games vs Philadelphia.