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The San Diego Padres take on the Philadelphia Phillies on Thursday night.

The San Diego Padres (44-27) are 11-1 in the 12 games that Joe Musgrove has pitched in this season ahead of Thursday night’s start against the Philadelphia Phillies (36-34). Musgrove and the Padres will look to keep things rolling as a Phillies vs Padres prediction favorite in San Diego.

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Phillies vs Padres Betting Preview

Phillies vs Padres Odds & Analysis

Opening Odds

The Phillies vs Padres predictions and bets have been fairly even on both sides in this National League matchup as the Padres opened at -148 and have settled in as -145 home favorites. The Phillies will try to pull off an upset as +135 underdogs while the total is set at 7 runs. The UNDER is 5-1 in San Diego’s last six games against Philadelphia.

Get the best Phillies vs Padres odds and lines available from our recommended sportsbooks for your favorite picks of the night.

  • Best Spread
    -160
    +145
    PHI+1.5
    -1.5SD
  • Best Moneyline
    +136
    -142
    PHI
    SD
  • Best Total
    +100
    -115
    Over7
    7Under

Starting Pitchers

Ranger Suarez pitched 5.2 innings and allowed six hits and three earned runs in a 5-3 Phillies win over the Washington Nationals last Friday night. Suarez has been better on the road this season with a 4-1 record and a 3.86 ERA compared to a 1-3 mark and a 5.10 ERA at home. He carries a 4.43 ERA and a 1.51 WHIP into this start against San Diego.

Joe Musgrove continued his dominant run last Thursday night against the Chicago Cubs, pitching seven innings and allowing only two runs with nine strikeouts. Musgrove has had a sensational 2022 campaign to date with an 8-0 record, a 1.59 ERA, a 0.92 WHIP and 81 strikeouts in 79 innings.

Philadelphia’s Offense Is Slumping This Week

The Phillies have been red-hot in June, opening the month with a nine-game winning streak and riding that into a 15-2 run to climb over .500 on the year. But that hot streak has given way to an 0-3 slump this week in which Philadelphia has been outscored 20-5. The club has averaged only 1.75 runs scored over its last four games.

Breaking out of this offensive slump against Joe Musgrove could be a tall order. Bettors taking Philadelphia as their Phillies vs Padres prediction may need Ranger Suarez to keep this one close enough to steal with a couple of runs.

San Diego Back On A Roll After Diamondbacks Sweep

The Padres had an 11-3 hot streak snapped when they got swept by the Colorado Rockies over the weekend. San Diego has bounced back from that sweep with one of their own, defeating Arizona three times this week to move to 44-27 on the season. The club is now 9-0 in its last nine games played against teams other than the Rockies.

Manny Machado has been out of the lineup with a sprained ankle since Sunday. Machado is expected to avoid a trip to the injured list, but he will be unavailable in Thursday’s game against the Phillies.

Phillies vs Padres Pick & Insights

Phillies: Keys To Victory

With Philadelphia’s offense slumping and Joe Musgrove on the mound, bettors shouldn’t expect the Phillies to record many runs in Thursday night’s series opener. The path to victory as a Phillies vs Padres prediction is to pitch well and to scratch out a low-scoring win.

Padres: Keys To Victory

Joe Musgrove has spent the last week on the COVID-19 injured list. He reportedly didn’t have any serious symptoms, so as long as the short stint out of the lineup doesn’t affect his performance, San Diego should feel confident about picking up a win as a Padres vs Phillies pick with their ace on the mound.

MLB Computer Pick: Padres -155 ML

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Shark Bites
  • Philadelphia is 15-5 in its last 20 games.
  • San Diego is 7-2 in its last 9 home games.
  • The UNDER is 4-1 in San Diego’s last 5 games.