FDU featured in our 1 vs 16 betting history

1 vs 16 Seed History: How Many 16 Seeds Beat A 1 Seed?

March Madness is here and we have our eight teams that will play in the 1 vs 16 games. The No. 1 seeds are: Auburn, Florida, Duke and Houston. While the No. 16 seeds are: Norfolk St, SIU Edwardsville, and then two representatives from the the First Four. 

Throughout college basketball history, seeing the No. 16 seed upset the No. 1 seed is a rare sight -- literally only two times. But, those exceptions occurred in the last decade—making those shocking upsets just a bit more realistic than usual. 

 

How many times has the no. 1 seed been upset by the no. 16 seed?

Expectedly, 1-seeds in March Madness hold a 154-2 all-time record against 16 seeds. Notably, the two upsets happened in the last five seasons. In 2018, UMBC shut down Virginia, 74-54, despite the Cavaliers being heavy 20.5-point favorites. Virginia entered The Dance as a No. 1 seed and ACC champions but the Retrievers effort marked the first upset in 1 vs 16 history.

Then, in more recent memory, FAU stunned Purdue in 2023. Zach Edey, a two-time National Player of the Year, was held to 21-points as the Knights rallied the 63-58 victory.

What Seed Has The Recent ATS Edge?

The 16-seeds historically have been overmatched, but the inflated lines have kept spread betting a bit more even. The No. 1 seeds are 84-70-2 ATS (54.4%) with 27 of the last 30 lines being set at 20-points or more. No. 16 seeds have covered the spread in five of the last 12 opening round matchups with No. 1 seeds. Though an outright victory mat be far-fetched, an ATS wager on the No.16 isn’t always a bad play.

Close Calls

We aren't typically holding our breath in these 1 vs 16 matchups. Before Virginia’s 2018 debacle, there were about five occasions where the No. 1 seed came nervously close to being upset by a No. 16 seed.

In 2014, No. 16 Albany nearly eliminated No. 1 Florida. The scoreboard was tied in the final 10 minutes before the Gators pulled off the 67-55 victory. 

In 1989, there were two meetings that ended in a one-point decision. No. 16 Princeton missed a final second shot to fall to No. 1 Georgetown, 50-49. Similarly, No. 16 ETSU didn't sink a basket in the dwindling seconds, giving No. 1 Oklahoma the 72-71 dub that same year.

Odds of 16 seed beating 1 seed

Of the 156 1 vs 16 matchups accounted for, mathematically, the No. 16 seed has a 1.28% chance of defeating the No. 1 seed outright in March Madness.

 

no. 1 seed vs no. 16 seed History

#1 Seed vs #16 Seed betting history
Year#1 SeedScore#16 SeedScoreDateATS WinWin SeedATS Seed
2025Houston SIU Edwardsville 2025-03-20   
2025Auburn Al St/SFPA 2025-03-20   
2025Florida Norfolk State 2025-03-21   
2025Duke AMER/MSM 2025-03-21   
2024Houston86Longwood462024-03-22Houston11
2024UConn91Stetson522024-03-22UConn11
2024North Carolina90Wagner622024-03-21North Carolina11
2024Purdue78Grambling502024-03-22Purdue11
2023Alabama96TAMU-CC752023-03-16TAMU-CC116
2023Purdue58FDU632023-03-17FDU1616
2023Kansas96Howard682023-03-16Kansas11
2023Houston63Northern Kentucky522023-03-17Northern Kentucky116
2022Gonzaga93Georgia State722022-03-17Georgia State116
2022Baylor85Norfolk State492022-03-17Baylor11
2022Arizona87Wright State702022-03-18Wright State116
2022Kansas83Texas Southern562022-03-17Kansas11
2021Illinois78Drexel492021-03-19Illinois11
2021Baylor79Hartford552021-03-19Hartford116
2021Michigan82Texas Southern662021-03-20Texas Southern116
2021Gonzaga98Norfolk State552021-03-20Gonzaga11
2019Gonzaga87Fairleigh Dickinson492019-03-21Gonzaga11
2019North Carolina88Iona732019-03-22Iona116
2019Duke85North Dakota State622019-03-22Iona116
2019Virginia71Gardner-Webb562019-03-22Gardner-Webb116
2018Villanova87Radford612018-03-15Villanova11
2018Kansas76Penn602018-03-15Kansas11
2018Virginia54UMBC742018-03-16UMBC1616
2018Xavier102Texas Southern832018-03-16Texas Southern116
2017Villanova76Mount St. Mary’s562017-03-16Villanova11
2017Kansas100UC Davis622017-03-17Kansas11
2017Gonzaga66South Dakota State462017-03-16South Dakota State116
2017North Carolina103Texas Southern642017-03-16North Carolina11
2016Virginia81Hampton452016-03-17Virginia11
2016Oregon91Holy Cross522016-03-18Oregon11
2016North Carolina83Florida Gulf Coast672016-03-17Florida Gulf Coast116
2016Kansas105Austin Peay792016-03-17Kansas11
2015Kentucky79Hampton562015-03-19Hampton116
2015Wisconsin86Coastal Carolina722015-03-20Coastal Carolina116
2015Villanova93Lafayette522015-03-19Villanova11
2015Duke85Robert Morris562015-03-20Duke11
2014Virginia70Coastal Carolina592014-03-21Coastal Carolina116
2014Wichita State64Cal Poly372014-03-21Wichita State11
2014Arizona68Weber State592014-03-21Weber State116
2014Florida67Albany552014-03-20Albany116
2013Kansas64Western Kentucky572013-03-22Western Kentucky116
2013Indiana83James Madison622013-03-22James Madison116
2013Louisville79North Carolina A&T482013-03-21Louisville11
2013Gonzaga64Southern582013-03-21Southern116
2012Michigan State89Long Island672012-03-16Michigan State11
2012North Carolina77Vermont582012-03-16North Carolina11
2012Kentucky81Western Kentucky662012-03-15Western Kentucky116
2012Syracuse72UNC Asheville652012-03-15UNC Asheville116
2011Kansas72Boston University532011-03-18Boston University116
2011Ohio State75Texas-San Antonio462011-03-18Ohio State11
2011Duke87Hampton452011-03-18Duke11
2011Pittsburgh74UNC Asheville512011-03-17Pittsburgh11
2010Syracuse79Vermont562010-03-19Syracuse11
2010Duke73Arkansas-Pine Bluff442010-03-19Duke11
2010Kansas90Lehigh742010-03-18Lehigh116
2010Kentucky100East Tennessee State712010-03-18Kentucky11
2009Louisville74Morehead State542009-03-20Morehead State116
2009Pittsburgh72East Tennessee State622009-03-20East Tennessee State116
2009Connecticut103Chattanooga472009-03-19Connecticut11
2009North Carolina101Radford582009-03-19North Carolina11
2008Memphis87Texas-Arlington632008-03-21Texas-Arlington116
2008North Carolina113Mount St. Mary’s742008-03-21North Carolina11
2008UCLA70Miss Valley State292008-03-20UCLA11
2008Kansas85Portland State612008-03-20Kansas11
2007Florida112Jackson State692007-03-16Florida11
2007Kansas107Niagara672007-03-16Kansas11
2007North Carolina86Eastern Kentucky652007-03-15Eastern Kentucky116
2007Ohio State78Cent Conn State572007-03-15Ohio State11
2006Connecticut72Albany592006-03-17Albany116
2006Villanova58Monmouth452006-03-17Monmouth116
2006Memphis94Oral Roberts782006-03-17Memphis11
2006Duke70Southern542006-03-16Southern116
2005Duke57Delaware State462005-03-18Delaware State116
2005North Carolina96Oakland682005-03-18PUSH1 
2005Illinois67Fairleigh Dickinson552005-03-17Fairleigh Dickinson116
2005Washington88Montana772005-03-17Montana116
2004Kentucky96Florida A&M762004-03-19Florida A&M116
2004Duke96Alabama State612004-03-18Duke11
2004Stanford71Texas-San Antonio452004-03-18Stanford11
2004Saint Joseph’s82Liberty632004-03-18Liberty116
2003Kentucky95IUPUI642003-03-21Kentucky11
2003Texas82UNC Asheville612003-03-21UNC Asheville116
2003Arizona80Vermont512003-03-20Arizona11
2003Oklahoma71South Carolina State542003-03-20South Carolina State116
2002Cincinnati90Boston University522002-03-15Cincinnati11
2002Maryland85Siena702002-03-15Siena116
2002Duke84Winthrop372002-03-14Duke11
2002Kansas70Holy Cross592002-03-14Holy Cross116
2001Illinois96Northwestern State542001-03-16Illinois11
2001Michigan State69Alabama State352001-03-16Michigan State11
2001Stanford89UNC Greensboro602001-03-15Stanford11
2001Duke95Monmouth522001-03-15Duke11
2000Duke82Lamar552000-03-17Lamar116
2000Stanford84South Carolina State652000-03-17South Carolina State116
2000Arizona71Jackson State472000-03-16Jackson State116
2000Michigan State65Valparaiso382000-03-16Michigan State11
1999Michigan State76Mount St. Mary’s531999-03-12Mount St. Mary’s116
1999Duke99Florida A&M581999-03-12Florida A&M116
1999Auburn80Winthrop411999-03-11Auburn11
1999Connecticut91Texas-San Antonio661999-03-11Texas-San Antonio116
1998Kansas110Prairie View A&M521998-03-13Kansas11
1998Duke99Radford631998-03-13Duke11
1998North Carolina88Navy521998-03-12North Carolina11
1998Arizona99Nicholls State601998-03-12Arizona11
1997Minnesota78Texas State461997-03-14Minnesota11
1997Kentucky92Montana541997-03-13Kentucky11
1997Kansas78Jackson State641997-03-13Jackson State116
1997North Carolina82Fairfield741997-03-13Fairfield116
1996Connecticut68Colgate591996-03-14Colgate116
1996Massachusetts92Central Florida701996-03-14Central Florida116
1996Kentucky110San Jose State721996-03-14Kentucky11
1996Purdue73Western Carolina711996-03-14Western Carolina116

The top seed has hoisted 26 national titles overall dating back to 1985. Over the past 17 years, a No. 1 seed has won the NCAA championship 13 times, including UConn’s 2024 triumph.

March Madness 1 vs 16 Betting History FAQ

Where can I bet on the 1 vs 16 seed March Madness game?

You can bet on the 1 vs 16 seed matchup of the NCAAB national championship tournament at a variety of betting sites. Luckily, Odds Shark has compiled a comprehensive list of the best March Madness betting sites with in-depth reviews, analysis, and perks of each site for experienced bettors and casual fans.

How do I bet on the 1 vs 16 seed March Madness game?

If you are researching how to bet on the 1 vs 16 seed March Madness matchup, look no further than Odds Shark. We have put together an expert How To Bet on March Madness guide that outlines how to read odds, the different betting formats available, and some March Madness betting strategy.

When was the last time a 16 seed beat a 1 seed in March Madness?

In 2023, Fairleigh Dickinson beat No. 1 seed Purdue, 63-58, to register the second 1 vs 16 upset in March Madness history. The first happened in 2018 when the University of Maryland, Baltimore County (UMBC) toppled No. 1 seed Virginia, 74-54.

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