Princeton Tigers featured in our March Madness 2 vs 15 betting history

March Madness Matchups: 2 vs 15 Betting History & Trends

In 10 March Madness brackets between 2002 and 2011, no No. 15 seed had upset a No. 2 seed. But since 2012, it has happened on seven occasions, throwing fear into bettors and destroying countless brackets.

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This year saw No. 15 Princeton shockingly eliminate the No. 2 Arizona Wildcats, who were among the top 10 for national championship odds (+1600) pre-tournament. The Wildcats entered the contest as heavy -1100 favorites, but it ended up being the Tigers who cashed in the +700 ML and covered the +14 spread in a 59-55 win.

In 2021, little-known Oral Roberts knocked off No. 2 Ohio State 75-72 as a whopping 16-point underdog. St. Peter’s was the Cinderella squad last year, toppling Kentucky as an 18.5-point underdog and cashing a +1000 moneyline. The Peacocks soared through the bracket all the way to the Elite Eight, where they got crushed by North Carolina. Still, there was magic in the air around that 15 spot. 

The 15 seed has gone 59-48-1 ATS against the 2 seed since 1996.

It was Norfolk State that pulled off the biggest 2 vs 15 upset in modern March Madness betting history, taking out Missouri 86-84 as a 21-point underdog in 2012. On the same day, Lehigh defeated Duke 75-70 as an 11-point underdog. Ironically, it was No. 7 seed Florida that ended Norfolk State’s run in the second round with an 84-50 victory as a 14-point favorite. Lehigh fell to No. 10 seed Xavier 70-58 in the second round as a 4-point underdog.

Only four other times in NCAA Tournament history prior to 2012 had there been an upset with a No. 15 seed defeating a No. 2. Richmond was the first to accomplish the feat in 1991 with a 73-69 victory against Syracuse.

Steve Nash’s Santa Clara team did it two years later with a 64-61 win over Arizona and then Coppin State posted the largest margin of victory ever for a No. 15 by routing South Carolina 78-65 in 1997. Four years after that, Hampton took out Iowa State by the smallest margin for a No. 15, 58-57.

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Who Has The Betting Edge In The 2 vs 15 matchup?

Backing the lower seed has been the way to go in the No. 2 vs No. 15 matchup as the No. 15 seed has gone 59-48-1 ATS since 1996. Since 2008, however, spread betting in this matchup has been a virtual coin flip with No. 15 having a minuscule 31-28-1 ATS edge. 

Seed vs Seed Stats: 1 vs 16 | 2 vs 15 | 3 vs 14 | 4 vs 13 | 5 vs 12 | 6 vs 11 | 7 vs 10 | 8 vs 9

#2 Seed vs #15 Seed
#2 SeedScore#15 SeedScoreDateATS WinWin SeedATS Seed
UCLA86UNC Asheville532023-03-17UCLA22
Kentucky79St. Peter’s852022-03-17St. Peter’s1515
Duke78Cal St. Fullerton612022-03-18Cal St. Fullerton215
Auburn80Jacksonville State612022-03-18Auburn22
Houston87Cleveland State562021-03-19Houston22
Ohio State72Oral Roberts752021-03-19Oral Roberts1515
Iowa86Grand Canyon742021-03-20Grand Canyon215
Kentucky79Abilene Christian442019-03-21Kentucky22
Michigan State76Bradley652019-03-21Bradley215
North Carolina84Lipscomb662018-03-16Lipscomb215
Purdue74Cal St. Fullerton482018-03-16Purdue22
Cincinnati68Georgia State532018-03-16Cincinnati22
Louisville78Jacksonville State632017-03-17Jacksonville State215
Arizona100North Dakota822017-03-16PUSH2PUSH
Kentucky79Northern Kentucky702017-03-17Northern Kentucky215
Michigan State81Middle Tennessee902016-03-18Middle Tennessee1515
Oklahoma82CSU Bakersfield682016-03-18CSU Bakersfield215
Xavier71Weber State532016-03-18Xavier22
Villanova86UNC Asheville562016-03-18Villanova22
Kansas75New Mexico State562015-03-20Kansas22
Arizona93Texas Southern722015-03-19Texas Southern215
Gonzaga86North Dakota State762015-03-20North Dakota State215
Kansas80Eastern Kentucky692014-03-21Eastern Kentucky215
Ohio State95Iona702013-03-22Ohio State22
Georgetown68Florida Gulf Coast782013-03-22Florida Gulf Coast1515
Missouri84Norfolk State862012-03-16Norfolk State1515
Ohio State78Loyola592012-03-15Ohio State22
North Carolina102Long Island872011-03-18Long Island215
Notre Dame69Akron562011-03-18Akron215
Florida79Santa Barbara512011-03-17Florida22
San Diego State68Northern Colorado502011-03-17San Diego State22
Ohio State68Santa Barbara512010-03-19Santa Barbara215
West Virginia77Morgan State502010-03-19West Virginia22
Kansas State82North Texas622010-03-18Kansas State22
Villanova73Robert Morris702010-03-18Robert Morris215
Michigan State77Robert Morris622009-03-20Michigan State22
Oklahoma82Morgan State542009-03-19Oklahoma22
Memphis81CS Northridge702009-03-19CS Northridge215
Texas74Austin Peay542008-03-21Texas22
Wisconsin76Texas A&M-CC632007-03-16Wisconsin22
Memphis73North Texas582007-03-16North Texas215
UCLA70Weber State422007-03-15UCLA22
Ohio State70Davidson622006-03-17Davidson215
Connecticut77Central Florida712005-03-18Central Florida215
Oklahoma State63Southeastern Louisiana502005-03-18Southeastern Louisiana215
Wake Forest70Chattanooga542005-03-17Chattanooga215
Kentucky72Eastern Kentucky642005-03-17Eastern Kentucky215
Mississippi State85Monmouth522004-03-19Mississippi State22
Oklahoma State75Eastern Washington562004-03-19Oklahoma State22
Florida85Sam Houston State552003-03-21Florida22
Wake Forest76East Tennessee State732003-03-21East Tennessee State215
Kansas64Utah State612003-03-20Utah State215
Alabama86Florida Atlantic782002-03-14Florida Atlantic215
Arizona101Eastern Illinois762001-03-16Arizona22
North Carolina70Princeton482001-03-16North Carolina22
Kentucky72Holy Cross682001-03-15Holy Cross215
Iowa State57Hampton582001-03-15Hampton1515
Cincinnati64UNC Wilmington472000-03-17UNC Wilmington215
St. John’s61Northern Arizona562000-03-16Northern Arizona215
Iowa State88Cent Conn State782000-03-16Cent Conn State215
Utah80Arkansas State581999-03-12Utah22
Stanford69Alcorn State571999-03-11Alcorn State215
Kentucky82South Carolina State671998-03-13South Carolina State215
Cincinnati65Northern Arizona621998-03-12Northern Arizona215
Connecticut93Fairleigh Dickinson851998-03-12Fairleigh Dickinson215
Duke71Murray State681997-03-14Murray State215
South Carolina65Coppin State781997-03-14Coppin State1515
UCLA109Charleston Southern751997-03-13UCLA22
Cincinnati66UNC Greensboro611996-03-15UNC Greensboro215
Georgetown93Miss Valley State561996-03-15Georgetown22
Kansas92South Carolina State541996-03-15Kansas22
Wake Forest64Northeast Louisiana501996-03-15Northeast Louisiana215

March Madness 2 vs 15 Betting History FAQ

Where can I bet on the 2 vs 15 seed March Madness games?

Experienced bettors and casual fans looking to bet on the 2 vs 15 seed March Madness games should refer to Odds Shark's Best March Madness Betting Sites Online guide. The guide reviews the top NCAAB tournament sportsbooks and gives insight into the best place to bet on March Madness this year.

How do I bet on the 2 vs 15 seed March Madness games?

There are multiple ways to bet on the 2 vs 15 seed March Madness games, including a moneyline bet, a spread bet, or many different props. Odds Shark's How to Bet on March Madness guide outlines all the bet formats you can utilize during the NCAAB tournament and some general March Madness betting tips for each.

When was the last time a 15 seed beat a 2 seed in March Madness?

The last time a 15 seed beat a 2 seed in March Madness was in 2023 when the underdog Princeton Tigers knocked off the No. 2 Arizona Wildcats 59-55 in the South Region.