Houston Astros at Chicago White Sox Betting Odds and Pick

The Chicago White Sox battle the visiting Houston Astros on Saturday in MLB betting odds action at Guaranteed Rate Field.

Chicago sends Lucas Giolito out against Dallas Keuchel for the Houston Astros in this game. Giolito is 0-2 with a 5.50 ERA on the season, while Keuchel is 0-3 on the year and has a 3.52 ERA.

Odds Shark prediction models pick the White Sox to win this game 4.1-3.2. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Houston Astros vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

4-12 Chicago battles the Astros, currently with a 14-7 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Houston injuries news.

The Odds Shark MLB Power Rankings have the Chicago White Sox at No. 27 and the Houston Astros at No. 7 heading into this contest.

Statistical Matchup

The game also pits Chicago White Sox No. 20-rated offense, averaging 3.88 runs per game, against a Houston Astros defense that ranks No. 1 at 2.62 in runs allowed per game. The Chicago White Sox have averaged 7.88 hits per game so far, less than Houston Astros batters have averaged on the year (8.38 hits per game).

Defensively, Houston features the No. 2-rated defense on the road, allowing 2.5 runs per game. Chicago, meanwhile, comes in at No. 29 at home, scoring 2.71 runs per game.