San Diego Padres at Houston Astros Betting Lines and Pick

Minute Maid Park hosts an MLB battle between the Houston Astros and the visiting San Diego Padres on Saturday.

The match puts starter Bryan Mitchell for the San Diego Padres on the hill facing Gerrit Cole for the Houston Astros. Mitchell brings a 0-1 mark to the game, while Cole is 1-0 to date on the season.

Sportsbook Odds & Computer Pick

Houston was a -270 moneyline favorites earlier in the day at Sportsbook, based on the starting pitcher matchup. That pairing made odds makers at Sportsbook pick an Sportsbook over under number of 8.5.

Handicapping models based on recent betting stats and prediction formulas pick a 9.5-0.4 win for the Astros. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs Houston Astros Matchup

Team Betting Records & Power Rankings

Houston (6-2) will face the 2-6 Padres in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and Houston vs San Diego injuries news.

The Odds Shark MLB Power Rankings have the Houston Astros at No. 1 and the San Diego Padres at No. 29 heading into this contest.

Statistical Matchup

At the plate, Houston owns the No. 11 ranking for hits at 8.75 per game. By contrast, the San Diego Padres are rated No. 18 in the same category at 8.12 per game.

Comparing defensive stats, San Diego owns the No. 1-rated road mark, allowing 1 runs per game on the highway. Houston, on the other hand, rates No. 11 in scoring at home.

Recent Outings Betting Recap

San Diego looks to continue its winning ways following a victory last time out against the Astros, a 4-1 final on Friday in support of Luis Perdomo at Minute Maid Park.

Betting Trends