San Francisco Giants at San Diego Padres Betting Lines and Pick

A key battle on the MLB betting odds menu sees the visiting San Francisco Giants dueling the San Diego Padres on Wednesday at PETCO Park.

Travis Wood gets the call for the San Diego Padres and he will try to build on a 3-4 mark. In the other dugout, Ty Blach brings a 8-10 ledger to the game for the San Francisco Giants as he tries to quiet the Padres bats.

Sportsbook Odds & Computer Pick

Those going with the San Diego Padres in this one found them listed on the odds board as moneyline favorites of -123 at Sportsbook for Wednesday's contest. The betting total was hovering near 8.5 at Sportsbook.

Handicapping models based on recent betting stats and prediction formulas pick a 4.7-4.1 win for the Giants. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Francisco Giants vs San Diego Padres Matchup

Team Betting Records & Power Rankings

San Diego (58-74) will face the 53-81 Giants in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Diego vs San Francisco injuries news.

This game puts the San Diego Padres, most recently No. 26 in Odds Shark MLB Power Rankings, up against the San Francisco Giants, who rate a No. 20 in the latest survey.

Statistical Matchup

At the plate, San Diego owns the No. 30 ranking for hits at 7.75 per game. By contrast, the San Francisco Giants are rated No. 20 in the same category at 8.54 per game.

Pitching and defensive stats are important baseball handicapping betting factors and San Diego has the No. 22-ranked defense. In the other dugout, the Giants own the No. 18 mark in runs allowed.