MLB Betting Line Favors the Chicago Cubs over the St. Louis Cardinals

MLB wagering interest swings to the St. Louis Cardinals vs Chicago Cubs battle on Wednesday at Wrigley Field as the Cubs try to pick up a win on home turf and reward those moneyline betting.

Chicago sends Jon Lester out against Luke Weaver for the St. Louis Cardinals in this game. Lester is 1-0 with a 4.40 ERA on the season, while Weaver is 2-0 on the year and has a 2.08 ERA.

Odds Shark computer prediction handicapping models run on this game pick a 5.0-3.6 victory for the Cubs. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

St. Louis Cardinals vs Chicago Cubs Matchup

Team Betting Records & Power Rankings

The Chicago Cubs bring a 7-8 record to the battle against the 10-7 Cardinals. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs St. Louis injuries news.

According to MLB Power Rankings here, it's the No. 9-ranked Chicago Cubs and the No. 15-rated St. Louis Cardinals in this matchup.

Statistical Matchup

At the plate, Chicago owns the No. 8 ranking for hits at 8.53 per game. By contrast, the St. Louis Cardinals are rated No. 10 in the same category at 8.24 per game.

Comparing defensive stats, St. Louis owns the No. 10-rated road mark, allowing 3.45 runs per game on the highway. Chicago, on the other hand, rates No. 5 in scoring at home.

Recent Outings Betting Recap

St. Louis looks to continue its winning ways following a victory last time out against the Cubs, a 5-3 final on Tuesday in support of A Wainwright at Wrigley Field.

Betting Trends