The top teams in college football will be looking to avoid Oregon's fate on Saturday as they hit the gridiron for a slate that features a half-dozen huge betting matchups.
Oregon's College Football Playoff hopes took a hit on Thursday night when they lost 31-24 to Arizona. The No. 2 Ducks are now in danger of sliding down the rankings and will be looking for other teams high in the polls to suffer upsets on Saturday.
Top-ranked Florida State is unlikely to fall on Saturday - they're 37.5-point home favorites against Wake Forest - but bettors are still waiting for them to pick up their first ATS victory of the season after they failed to cover in their first four outings. The Seminoles are 4-1 ATS in their last five games against the Demon Deacons.
Matchup Reports: WF vs. Florida State | Alabama vs. Ole Miss | Stanford vs. Notre Dame
No. 3 Alabama will try to capitalize on Oregon's stumble this weekend, but they'll have to do it against a tough opponent in No. 11 Ole Miss. Alabama is just 1-4 ATS in its last five road games, while Ole Miss has managed to pay off in six of its last nine games against Alabama.
Other ranked matchups on Saturday include No. 4 Oklahoma at No. 25 TCU, No. 6 Texas A&M at No. 12 Mississippi State, No. 15 LSU at No. 5 Auburn, No. 19 Nebraska at No. 10 Michigan State, and No. 14 Stanford at No. 9 Notre Dame.
The Fighting Irish have paid off on the college football betting lines in each of their last three home games, but Stanford is 3-1 ATS in its last four games against Notre Dame in this rivalry series. The UNDER has gone 11-2 in Stanford's last 13 games on the road for totals bettors.
Week 6 College Football Betting Content at OddsShark