The Houston Texans will be gunning for their fifth straight ATS victory of the season on Monday night as a big road favorite to highlight the NFL's Week 5 Sportsbook lines at the sportsbooks.
Houston is 4-0 both ATS and SU atop the league standings this season, and they opened as favorites of +9 at Sportsbook against the New York Jets for their Monday Night Football matchup.
The Jets are one of several teams to open as home underdogs for Week 5, with that list also including the Colts +7.5 vs. the Packers, the Jaguars +5.5 vs. the Bears, the Chiefs +4.5 vs. the Ravens, and the Redskins +3 vs. the Falcons.
As well, the Rams opened at +1 at home against the Cardinals for Thursday Night Football this week, with Arizona 4-1 both SU and ATS over their past five games against St. Louis. The OVER/UNDER went 1-4 in those five contests.
The biggest favorite on the Sportsbook lines at Sportsbook for Week 5 are the New York Giants at -11 at home against the Browns - who are 0-4 SU but 2-1-1 ATS on the season.
Week 5 Sportsbook NFL Betting Lines (from Sportsbook)
Thu - Arizona at St. Louis (+1) (8:20pm ET)
Sun - Miami at Cincinnati (-4.5) (1:00pm ET)
Sun - Green Bay at Indianapolis (+7.5) (1:00pm ET)
Sun - Baltimore at Kansas City (+4.5) (1:00pm ET)
Sun - Tennessee at Minnesota (-5) (1:00pm ET)
Sun - Atlanta at Washington (+3) (1:00pm ET)
Sun - Cleveland at NY Giants (-11) (1:00pm ET)
Sun - Philadelphia at Pittsburgh (-3.5) (1:00pm ET)
Sun - Seattle at Carolina (-3) (4:05pm ET)
Sun - Chicago at Jacksonville (+5.5) (4:05pm ET)
Sun - Denver at New England (-7.5) (4:25pm ET)
Sun - Buffalo at San Francisco (-10) (4:25pm ET)
Sun - San Diego at New Orleans (-3) (8:20pm ET)
Mon - Houston at NY Jets (+9) (8:30pm ET)
Week 5 NFL Betting Trends and Notes
Arizona at St. Louis
Arizona is 5-0 SU in its last 5 games
The total has gone UNDER in 7 of St. Louis's last 8 games when playing Arizona
Philadelphia at Pittsburgh
Philadelphia is 7-1 SU in its last 8 games
Pittsburgh is 11-1 SU in its last 12 games at home
Miami at Cincinnati
Miami is 6-1 SU in its last 7 games when playing on the road against Cincinnati
The total has gone OVER in 7 of Cincinnati's last 8 games at home
Atlanta at Washington
Atlanta is 5-1 SU in its last 6 games
The total has gone OVER in 5 of Washington's last 5 games at home
Green Bay at Indianapolis
Green Bay is 21-4 SU in its last 25 games
The total has gone UNDER in 6 of Indianapolis's last 7 games
Baltimore at Kansas City
The total has gone UNDER in 5 of Baltimore's last 6 games when playing on the road against Kansas City
The total has gone UNDER in 5 of Kansas City's last 6 games when playing at home against Baltimore
Cleveland at NY Giants
The total has gone UNDER in 5 of Cleveland's last 6 games
The total has gone UNDER in 5 of the NY Giants last 6 games
Seattle at Carolina
The total has gone UNDER in 5 of Seattle's last 6 games
The total has gone OVER in 8 of Carolina's last 11 games
Chicago at Jacksonville
Chicago is 4-1 SU in its last 5 games
The total has gone UNDER in 4 of Jacksonville's last 5 games
Buffalo at San Francisco
The total has gone OVER in 6 of Buffalo's last 7 games
San Francisco is 8-1 SU in its last 9 games at home
Denver at New England
Denver is 17-6 SU in its last 23 games when playing New England
New England is 17-4 SU in its last 21 games at home
Tennessee at Minnesota
The total has gone OVER in 5 of Tennessee's last 6 games
Minnesota is 5-1 SU in its last 6 games when playing at home against Tennessee
San Diego at New Orleans
The total has gone OVER in 6 of San Diego's last 7 games when playing New Orleans
The total has gone OVER in 8 of New Orleans's last 9 games
Houston at NY Jets
Houston is 5-1 SU in its last 6 games
NY Jets are 5-0 SU in their last 5 games when playing Houston