The UFC returns to T-Mobile Arena in Las Vegas, Nevada, for the first time in 16 months for a big event. UFC 264 is headlined by the trilogy match between the promotion’s biggest star, Conor McGregor, and Dustin Poirier.
In that big main event, the McGregor vs Poirier 3 odds are currently set with Poirier the betting favorite over McGregor.
McGregor has been very inactive of late, with this being just his fourth fight since the start of 2017, and he holds a 1-2 record in his last three, including the knockout loss to Poirier in January.
Poirier avenged his 2014 defeat to McGregor with his victory at UFC 257 and looks to close that chapter and return to a title fight with another statement win over the Irishman.
UFC 264 Odds: McGregor vs Poirier 3
Online sportsbook Bovada has released the UFC 264 odds with Dustin Poirier holding -120 odds and Conor McGregor coming back at +100. This means you would have to wager $120 to profit $100 with a Poirier win, while a $100 bet on a McGregor victory would profit you $100.
Looking at the UFC 264 odds for McGregor vs Poirier 3, our sports betting calculator tells us that Poirier’s odds of -120 represent an implied win probability of 54.55 percent while McGregor’s +100 odds have an implied win probability of 50.00 percent.
The largest favorite in the UFC 264 odds is in the opening fight of the main card with Sean O’Malley (-900) favored over UFC newcomer Kris Moutinho (+550).
The tightest UFC 264 betting line comes in the middleweight prelim fight with Dricus Du Plessis (-115) slightly favored over Trevin Giles (-105).
UFC 264 Betting Odds & Fight Card
Ready to make a UFC 264 bet but are new to betting on the fights? Our How to Bet on the UFC guide will provide you with everything you need to know about betting on the fights. Also, be sure to visit Odds Shark's UFC fight analysis page as well as our UFC odds page for current UFC 264 betting lines.
Conor McGregor vs Dustin Poirier 3 Odds & Prediction
The “Notorious” Conor McGregor (+100) looks to avoid his first-ever losing streak and return to the win column for the first time in 19 months. Meanwhile, Dustin “The Diamond” Poirier (-120) eyes a third straight victory since he lost to Khabib Nurmagomedov in September 2019.
For more on this fight, see the McGregor vs Poirier 3 odds analysis article.
Prediction: Conor McGregor (+100) via knockout
Gilbert Burns vs Stephen Thompson Odds & Prediction
After losing to Kamaru Usman for the welterweight championship in February, Gilbert “Durinho” Burns (+140) looks to rebound and get back to his winning ways. Stephen “Wonderboy” Thompson (-170) was 0-1-1 in his two attempts at winning UFC gold but after back-to-back wins, a win over Burns could get him a third attempt at the belt.
Prediction: Stephen Thompson (-170) via decision
Tai Tuivasa vs Greg Hardy Odds & Prediction
Following a three-fight losing skid, Tai “Bam Bam” Tuivasa (-140) now eyes a three-fight winning streak after picking up back-to-back first-round knockouts heading into this bout. Conversely, Greg “The Prince of War” Hardy (+115) comes in on the heels of his first knockout loss, at the hands of Marcin Tybura in December.
Prediction: Greg Hardy (+115) via decision
Irene Aldana vs Yana Kunitskaya Odds & Prediction
Yana Kunitskaya (+100) returns to the Octagon for the second time this year as she eyes her first three-fight winning streak in nine years, coming off back-to-back impressive decision wins. Meanwhile, Irene Aldana (-120) faltered in her attempt at a three-fight winning streak in her last appearance, getting outclassed by former champion Holly Holm.
Prediction: Yana Kunitskaya (+100) via decision
Sean O’Malley vs Kris Moutinho Odds & Prediction
After original opponent Louis Smolka pulled out, “Sugar” Sean O’Malley (-900) called for any opponent so that he could get back on a winning streak following a knockout win in March. Ready to make his UFC debut in a big way is Kris Moutinho (+550), who has won his last two fights by stoppage.
Prediction: Sean O’Malley (-900) via knockout
UFC 264: McGregor vs Poirier 3 Best Bets
Doc's Picks Service
Need more winning picks? Get $60 worth of premium member picks from Doc’s Sports – a recognized leader and trusted name in sports handicapping since 1971.