OddsShark Top Sportsbooks

*Terms and Conditions apply to all bonus offers on this website. Please visit operator for details.

San Francisco Favored by -3.5 Against Arizona on Sunday - Week 17 NFL Betting Odds and Pick

Arizona Cardinals


San Francisco 49ers
Sunday, December 28, 2014 4:25 PM ET
Levi's Stadium

Riddled with injuries at quarterback, the Arizona Cardinals could turn to rookie Logan Thomas this Sunday under center. Arizona hopes to build some momentum on offense heading into the postseason going up against the San Francisco 49ers this week.

San Francisco is 5-4 SU and 1-8 ATS in its last nine home games and 5-2-1 SU and 2-6 ATS in its last eight home games against NFC West opponents. The Cardinals are just 3-9 SU and ATS in their last 12 games against San Francisco. The UNDER is 4-0 in San Francisco's last four divisional home games.

Arizona Cardinals vs San Francisco 49ers Opening Odds and Betting Line

Betting fans looking to side with the San Francisco 49ers in this one found them as -3.5-point favorites earlier in the week at Bovada, while the total was sitting at 36.5.

Computer Prediction: Arizona Cardinals vs San Francisco 49ers Pick

Odds Shark score prediction models pick a 19-15 result in favor of the Cardinals on Sunday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.

Arizona Cardinals vs San Francisco 49ers Odds and Stats.

Team Betting Records & Power Rankings

San Francisco will face the 11-4 Arizona Cardinals, who own a 10-5 ATS mark on the season. In totals betting, the 49ers are 5-10 so far this season while the Cardinals are 5-9-1. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Francisco vs Arizona injuries news.

It's a betting matchup between the No. 23-rated San Francisco 49ers and the No. 19-ranked Arizona Cardinals, according to the NFL Power Rankings here at Odds Shark.

How Arizona Cardinals vs San Francisco 49ers Stats Matchup

Offensively, the game matches up the San Francisco 49ers No. 26-ranked offense (19.07 PPG) against a Arizona Cardinals defense that ranks No. 4 at 18.6 PPG. The 49ers passing attack has averaged 191.6 yards per game, less than the Cardinals give up through the air (264.2 YPG on average).

In comparing defenses, the Arizona Cardinals own the league's No. 5-rated front 7 in terms of stopping the run, allowing 93.71 yards per game when on the road. San Francisco, on the other hand, rates No. 2 this week in generating rushing yards at home.

Recent Outings Betting Recap

Arizona was hamered in its last outing, as Seattle ran up a 35-6 score against them at University of Phoenix Stadium.

Frank Gore tore up the turf for 158 rushing yards in the latest 49ers game, a 38-35 loss to the Chargers at Levi's Stadium.

Arizona Cardinals vs San Francisco 49ers Betting Odds Trends

Arizona is 8-3 ATS in its last 11 games
Arizona is 18-6 SU in its last 24 games
The total has gone UNDER in 4 of Arizona's last 6 games
Arizona is 6-3 ATS in its last 9 games on the road
San Francisco is 0-5 ATS in its last 5 games
San Francisco is 1-4 SU in its last 5 games
The total has gone UNDER in 5 of San Francisco's last 6 games
San Francisco is 1-8 ATS in its last 9 games at home

Next Betting Matchups

Arizona home to , Wednesday, December 31st
San Francisco home to , Wednesday, December 31st