Dolphins vs 49ers Picks & Odds: 49ers Favored In Clash Of Red-Hot Teams

The San Francisco 49ers (7-4 SU, 6-5 ATS) are 7-2-1 ATS in their last 10 games against the Miami Dolphins (8-3, 6-5), though the Dolphins hold a 4-1 SU advantage in the last five games of the head-to-head series. The 49ers will be looking for their fifth straight win Sunday afternoon in San Francisco.

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Dolphins vs 49ers Sportsbook Odds

The 49ers opened as 5-point home favorites before betting action on Miami shifted the Dolphins vs 49ers odds down to San Francisco -3.5. The total in this highly anticipated matchup has settled in at 46.5 points since Sportsbook at 45.5 points. The UNDER is 6-1 in San Francisco’s last seven games against AFC teams.

Get the best Dolphins vs 49ers odds and lines available from our recommended sportsbooks for your favorite picks of the night.

Miami Is Undefeated Since Tua Tagovailoa’s Return To Action

The Dolphins jumped out to a 30-0 lead by halftime and coasted to a 30-15 win at home over the Houston Texans last Sunday. Tua Tagovailoa went 22-for-36 with 299 passing yards and a touchdown pass in the win. Miami’s talented wide receiving duo of Tyreek Hill and Jaylen Waddle each recorded 85 receiving yards against the Texans. Raheem Mostert missed the game with a knee injury and is questionable to return against his former team.

Tagovailoa took a scary hit in Miami’s 27-15 loss to the Cincinnati Bengals back on September 9, knocking him out of action with a concussion for the next two games. Since his return on October 23, the Dolphins are 5-0 SU and 3-2 ATS. The 24-year-old quarterback is enjoying a breakout season with 2,564 passing yards, 19 touchdown passes and three interceptions in nine games.

San Francisco’s Defense Has Been Excellent During Recent Hot Streak

On a day when the 49ers couldn’t get much going with their offense, the defense led the way in a 13-0 road win over the New Orleans Saints. San Francisco limited the Saints to 260 total yards and forced two turnovers in the shutout win. The 49ers are now 4-0 SU and 3-1 ATS over their last four games, with their defense allowing only 10 points per game over that stretch.

Christian McCaffrey was surprisingly quiet against New Orleans with only 49 total yards from scrimmage on 11 carries and four receptions. McCaffrey may take on a bigger role this Sunday as Elijah Mitchell is set to miss six to eight weeks with a knee injury sustained in the win. San Francisco had averaged 30.3 points per game over its previous three games prior to only scoring 13 against New Orleans.

Dolphins: Keys to Win

Miami’s offense has been unstoppable in recent weeks, averaging 33.8 points per game over the team’s last four outings. Tagovailoa and the Dolphins will face a tough test against this 49ers defense on Sunday, and passing that test with another strong day on offense will be key to winning as a Dolphins vs 49ers prediction.

49ers: Keys to Win

San Francisco’s offense hit a wall last Sunday against New Orleans, and losing Elijah Mitchell won’t help matters. The 49ers defense is good enough to at least slow down this impressive Miami offense, but to win and cover as a Dolphins vs 49ers pick, San Francisco is going to need to bounce back on offense this weekend.

NFL Computer Pick: 49ers -3.5

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