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Underachieving Cardinals Host Toothless Niners in NFC West Clash

David Johnson Cardinals

Winless straight up in their past two, the Arizona Cardinals will be looking to bolster their fading playoff hopes when they host the free-falling San Francisco 49ers on Sunday afternoon in a Week 10 clash of NFC West rivals at University of Phoenix Stadium.

Shark Bites
  • The total has gone OVER in seven of the Cardinals' last eight games in Week 10.
  • The Cardinals are 7-1 SU in their last eight games with a closing total of 48.0 or more.
  • The 49ers are 2-7 SU in their last nine games against their division.

The Cardinals entered a bye last week following a 30-20 loss in Carolina as 2.5-point underdogs that dropped them to 3-4-1 on the season. Arizona has been a dicey bet on home turf, going 3-9 ATS in its past 12 overall in the desert. The Cardinals are a solid 7-2 SU in their past  nine as double-digit chalk, but have covered just once in their past six.

The 49ers are coming off their seventh straight SU and ATS loss, a 41-23 beating by the New Orleans Saints as 5-point home underdogs. San Francisco has surrendered 33 or more points in six of those seven losses, pushing the point total OVER on six occasions despite averaging fewer than 20 ppg during that stretch.

Arizona has dominated in recent matchups with their divisional rivals, going 4-1 SU and ATS in their past five, including a devastating 47-7 home victory last season as 7-point chalk, and has held the 49ers to 15 ppg during that span.

Opening Odds & Computer Pick

On the opening betting line for this matchup, the Arizona Cardinals sat as -12.5-point favorites at shops such as BetOnline. The total, has been pegged by the odds makers at GTbets.eu at 48.

Odds Shark computer score prediction models pick a possible 36-10 win for the Cardinals on Sunday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.

San Francisco 49ers vs Arizona Cardinals Matchup

Team Betting Records & Power Rankings

The San Francisco 49ers will look to cover ATS vs their hosts on Sunday, as they are 1-7 ATS versus the spread this season, while the Arizona Cardinals are 3-5 ATS. San Francisco is 6-2 against the over under total, while Arizona is 3-4-1 versus the number. Stay Informed: follow us on Twitter for odds specials, betting line moves and Arizona vs San Francisco injuries news.

The Odds Shark Power Rankings have the Arizona Cardinals at No. 8 and the San Francisco 49ers at No. 32 heading into this contest.

Statistical Matchup

Offensively, the game matches up the Arizona Cardinals No. 19-ranked offense (22.38 PPG) against a San Francisco 49ers defense that ranks No. 32 at 32.5 PPG. The Cardinals passing attack has averaged 258.88 yards per game, more than the 49ers give up through the air (235 YPG on average).

Defensively, the San Francisco 49ers feature the league's No. 32-rated road run defense, allowing 205 yards per game. The Arizona Cardinals, meanwhile, ranks No. 12 in rushing offense at home.

Recent Outings Betting Recap

In their last game, San Francisco's aerial attack generated 398 yards but it was the Saints coming away with a 41-23 victory over San Francisco at Levi's Stadium.

Betting Trends
  • San Francisco is 0-5 ATS in its last 5 games
  • San Francisco is 0-5 SU in its last 5 games
  • The total has gone OVER in 6 of San Francisco's last 7 games
  • San Francisco is 0-5 ATS in its last 5 games on the road
  • Arizona is 3-8 ATS in its last 11 games
  • Arizona is 2-3-1 SU in its last 6 games
  • Arizona is 3-9 ATS in its last 12 games at home
  • Arizona is 16-5-1 SU in its last 22 games at home

Next Betting Matchups

San Francisco home to New England, Sunday, November 20th
Arizona at Minnesota, Sunday, November 20th