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San Francisco has enjoyed success against Los Angeles

The San Francisco 49ers are 5-2 SU and ATS in their last seven games against the Rams with wins in each of the last two games in this head-to-head series. The 49ers will try to pick up a third straight win over the Rams on Saturday in Los Angeles.

  • The total has gone UNDER in the 49ers' last four games against the Rams.
  • The Rams are 3-1 SU and ATS in their last four games in Week 16.
  • The 49ers are 0-10 SU and 0-9-1 ATS in their last 10 games after winning the previous game in a matchup.

The 49ers crushed the Rams 28-0 in their season opener at home. Since then, San Francisco has gone an abysmal 0-13 SU and 1-11-1 ATS over its last 13 games. The 49ers are 0-16 SU and 1-14-1 ATS in their last 16 games against teams that aren't the Rams and 2-0 SU and ATS in their last two games against the Rams.

Los Angeles fired Jeff Fisher on the heels of a third straight blowout loss against Atlanta, but that didn't prevent the Rams from suffering a fourth straight blowout. The Rams lost 24-3 on the road to Seattle, falling to 0-5 SU and ATS over their last five games and 1-9 SU and 1-8-1 ATS over their last 10.

Opening Odds & Computer Pick

The Los Angeles Rams were -3-point favorites at odds maker shops such as Bovada, while the NFL total was set at 41 for over under totals betting.

Odds Shark prediction models picked the Rams to win this game on Saturday 26-14. Check the picks page or matchup report during the week as factors may cause that prediction to be re-run. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.

San Francisco 49ers vs Los Angeles Rams Matchup

Team Betting Records & Power Rankings

Los Angeles will face the 1-13 San Francisco 49ers, who own a 2-11-1 ATS mark on the season. In totals betting, the Rams are 5-9 so far this season while the 49ers are 8-6. Stay Informed: follow us on Twitter for odds specials, betting line moves and Los Angeles vs San Francisco injuries news.

According to the Power Rankings here at Odds Shark it's the No. 29-rated Los Angeles Rams and the No. 32-rated San Francisco 49ers in this matchup.

Statistical Matchup

Offensively, the game matches up the Los Angeles Rams No. 32-ranked offense (14.07 PPG) against a San Francisco 49ers defense that ranks No. 32 at 31 PPG. The Rams passing attack has averaged 200.14 yards per game, less than the 49ers give up through the air (248.64 YPG on average).

Defensively, the San Francisco 49ers feature the league's No. 32-rated road run defense, allowing 158 yards per game. The Los Angeles Rams, meanwhile, ranks No. 30 in rushing offense at home.

Recent Outings Betting Recap

Carlos Hyde went over the 100-yard mark (193) in his team's latest effort, but New York still defeated San Francisco by a score of 23-17.

Los Angeles didn't make much of a game of it last time out, losing to the Falcons as Atlanta blasted them 42-14 in Week 14 action.

Betting Trends
  • San Francisco is 0-4-1 ATS in its last 5 games
  • San Francisco is 0-5 SU in its last 5 games
  • The total has gone UNDER in 4 of San Francisco's last 6 games
  • San Francisco is 1-7-1 ATS in its last 9 games on the road
  • Los Angeles is 0-5 ATS in its last 5 games
  • Los Angeles is 0-5 SU in its last 5 games
  • The total has gone UNDER in 6 of Los Angeles's last 8 games
  • Los Angeles is 0-4-1 ATS in its last 5 games at home

Next Betting Matchups

San Francisco home to Seattle, Sunday, January 1st
Los Angeles home to Arizona, Sunday, January 1st