The Los Angeles Rams lead NFC West odds.

NFC West Odds & Betting Preview: Rams Still Favorites

Maybe the best division in football last season, the NFC West produced three playoff teams in 2021, including the eventual Super Bowl champion L.A. Rams.

In 2022, the division is expected to be hotly contested once again with oddsmakers thinking the Rams are the most likely Sportsbooks at +125, followed by the San Francisco 49ers (+150) and Arizona Cardinals (+450). The Seattle Seahawks were the only team in the West to start the season with a win, but they still find themselves as +1200 underdogs.

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NFC West Odds: Rams On Top

Odds To Win NFL - NFC West Division 2023-24
San Francisco 49ers-165
Seattle Seahawks+250
LA Rams+575
Arizona Cardinals+2000

Odds as of May 17th, 2023 12:42pm EDT.

Los Angeles Rams (+125)

Like most teams following a Super Bowl victory, the Rams lost a few players from their roster as other teams looked to poach some title Sportsbooks. The Rams lost receivers Odell Beckham Jr. and Robert Woods, star pass rusher Von Miller, starting cornerback Darious Williams and others to free agency, along with left tackle Andrew Whitworth to retirement. 

But, they still have Matthew Stafford. They still have Aaron Donald. They still have Cooper Kupp. They still have Jalen Ramsey. And they’re still coached by Sean McVay. This is one of the better rosters in the league despite the losses, and they made a couple of big additions in receiver Allen Robinson and linebacker Bobby Wagner. 

Even with a tough Week 1 loss to the Bills to start their campaign, the Rams should still finish with around 11-13 wins once again and are a legitimate Super Bowl repeat threat in a weaker NFC.


San Francisco 49ers (+150) 

After finishing 11-6 last season, the Niners came within one win of another Super Bowl berth before losing to the rival Rams in the NFC championship game.

This season the Niners return one of the best rosters in the league with one of the best coaches, but there’s one big question mark looming over the Bay Area.

Though Jimmy Garoppolo led the team to the conference championship game last season, young QB Trey Lance has taken the reins under center in 2022. Lance is raw but talented, with arm strength and athleticism to spare. But, the inexperience flashed brighter than the talent in San Fran’s Week 1 loss to the lowly Bears.

San Francisco’s season in some ways hinges on the young QB’s development, and we aren’t ready to bet on them winning the division with essentially a rookie at QB.


Arizona Cardinals (+450)

We feel better about Arizona’s NFC West odds because they at least have a QB we know is good.

Kyler Murray is one of the better quarterbacks in the NFL and we know he can put points on the board through the air and on the ground. While the Cardinals may not be as complete a team as the Rams, they do have the upside talent to match the NFC’s best, including J.J. Watt, Marquise Brown, Zach Ertz and more.

The Cards do have some question marks on defense and they’ll be without star receiver DeAndre Hopkins for the first six games of the season due to suspension. But, if everything breaks right, Arizona has what it takes to win a division and +450 is pretty nice value.


Seattle Seahawks (+1200)

The Seahawks entered the 2022 season with low expectations. Perceived to have maybe the worst roster top to bottom, including likely the worst quarterback situation in the league, there wasn’t much hope for Seattle.

However, Geno Smith and the Seahawks shocked the Broncos in Week 1 and showed some unexpected signs of life. It’s probably asking too much for the Seahawks to continue shocking teams on their way to a division title, but Seattle may be a bit better than we thought.

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Best NFC West Odds Bet: Arizona Cardinals (+450)

The Rams will probably end up winning this division, but the Cardinals are the best value. With the skill position talent to match any other team in this division, Arizona just needs to stay healthy and win some divisional games to upset L.A.

Understanding NFC West Odds

When you visit any NFL sportsbooks, you’ll notice the odds appear like they do in our chart. The team with the minus sign (-) in front of its odds is the favorite. The rest are underdogs. In some cases, especially in August, you may not see any minus signs. In scenarios like that, the squad with the lowest odds is the fave.

Let’s say you’re looking at Arizona at -375. If you were to lay down $100, you’d get a payout of $126.67 – your $100 is returned along with your winnings of $26.67. On the other hand, you may look at Los Angeles at +300 and think they’re going to win the division. That same $100 would give you a payout of $400 – your original money comes back to you, coupled with your winnings of $300.


Our Odds Calculator will show you what you’d win based on the odds and amount bet.

Underdogs are a riskier bet, which is why they come with a bigger reward. However, don’t bet on them blindly, especially if their odds are too high. When oddsmakers create futures betting lines, they look at everything, including schedule, past performances and roster moves.

What Is An NFL Futures Bet?

To place a bet on NFC West odds, you would be making a futures bet. This is a wager made weeks or even months in advance of the end of the NFL season on which team you think has the best odds of becoming divisional champion.

We suggest taking odds you like right away. The lines will move as injuries happen, coaches are fired, and teams move up or down in the standings. You don’t want to miss out on great odds.