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Maybe the best division in football last season, the NFC West produced three playoff teams, including the eventual Super Bowl champion L.A. Rams.

This season, the division is expected to be hotly contested once again with oddsmakers thinking the Rams are the most likely winners at +135, followed by the San Francisco 49ers (+215), Arizona Cardinals (+275) and Seattle Seahawks (+900).

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NFC West Odds: Rams On Top

Odds to Win the NFC West in 2022
Team Opening Odds
Los Angeles Rams +135
San Francisco 49ers +215
Arizona Cardinals +275
Seattle Seahawks +900

Odds as of July 11 at BetOnline Sportsbook

Los Angeles Rams (+135)

Like most teams following a championship victory, the L.A. Rams lost a few players from their roster as other teams looked to poach some title winners. The Rams lost receivers Odell Beckham Jr. and Robert Woods, star pass rusher Von Miller, starting cornerback Darious Williams and others to free agency, along with left tackle Andrew Whitworth to retirement. 

But, they still have Matthew Strafford. They still have Aaron Donald. They still have Cooper Kupp. They still have Jalen Ramsey. And they’re still coached by Sean McVay. This is one of the better rosters in the league despite the losses, and they even made a couple of big additions in receiver Allen Robinson and linebacker Bobby Wagner. 

The Rams should finish with around 11-13 wins once again and are a legitimate Super Bowl repeat threat in a weak NFC.

San Francisco 49ers (+215) 

After finishing 11-6 last season, the Niners came within one win of another Super Bowl berth before losing to the rival Rams in the NFC championship game.

This season the Niners return one of the best rosters in the league with one of the best coaches, but like many other teams around the league, they have question marks at quarterback.

Jimmy Garoppolo led the team to the championship game last season, but 2021 top-three pick Trey Lance is waiting in the wings. The expectation is that this is now Lance’s team as trade rumors once again swirl around Garoppolo’s name. Lance is raw but talented, with arm strength and athleticism to spare.

San Francisco’s season in some ways hinges on the young QB’s development, and we aren’t ready to bet on them winning the division with essentially a rookie at QB.

Arizona Cardinals (+275)

We feel better about Arizona’s NFC West odds because they at least have a QB we know is good. At least for now… 

Kyler Murray is one of the better quarterbacks in the NFL and we know he can put points on the board through the air and on the ground. But a contentious contract negotiation has some questioning when and if Murray will show up on the field for training camp with his team. Insiders seem to believe a deal gets done sometime this summer, but until it does, there will be questions about how this hurts the team. 

Besides Murray, the Cards are solid. They have some questions marks on defense and they’ll be without star receiver DeAndre Hopkins for the first six games of the season due to suspension. But the Cards are good enough to be back in the playoffs.

We aren’t sure +275 is steep enough for a sprinkle on the division title, though.

Seattle Seahawks (+900)

With maybe the worst roster top to bottom, including likely the worst quarterback situation in the league, there’s not much to say about this Seahawks team.

A once elite roster has been whittled to the bone by Pete Carroll, John Schneider and the Seahawks brass. They will run the ball a lot, won’t score a lot of points and won’t be able to stop anyone.

+900 is generous.

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Understanding NFC West Odds

When you visit any NFL sportsbooks, you’ll notice the odds appear like they do in our chart. The team with the minus sign (-) in front of its odds is the favorite. The rest are underdogs. In some cases, especially in August, you may not see any minus signs. In scenarios like that, the squad with the lowest odds is the fave.

Let’s say you’re looking at Arizona at -375. If you were to lay down $100, you’d get a payout of $126.67 – your $100 is returned along with your winnings of $26.67. On the other hand, you may look at Los Angeles at +300 and think they’re going to win the division. That same $100 would give you a payout of $400 – your original money comes back to you, coupled with your winnings of $300.

Our Odds Calculator will show you what you’d win based on the odds and amount bet.

Underdogs are a riskier bet, which is why they come with a bigger reward. However, don’t bet on them blindly, especially if their odds are too high. When oddsmakers create futures betting lines, they look at everything, including schedule, past performances and roster moves.

What Is An NFL Futures Bet?

To place a bet on NFC West odds, you would be making a futures bet. This is a wager made weeks or even months in advance of the end of the NFL season on which team you think has the best odds of becoming divisional champion.

We suggest taking odds you like right away. The lines will move as injuries happen, coaches are fired, and teams move up or down in the standings. You don’t want to miss out on great odds.